Doxycycline hyclate 100 mg
Doxycycline is a tetracycline antibiotic taken by mouth. It is prescribed for a wide range of bacterial infections, for some sexually transmitted infections, as an add-on in severe acne, and to help prevent malaria in travellers. It has no effect on viruses, and it is available only on a valid prescription.
This medicine is dispensed only against a valid prescription. Don’t have one? Order anyway — one of our doctors will call you for a free consultation after you order, and the medicine ships only if it is prescribed for you.
A licensed pharmacist reviews every prescription before this medicine is dispensed.
How it works- Pharmacist checked Every order reviewed
- Tracked delivery Tracked to your door
- Genuine packaging Sealed and verified
- Licensed pharmacy Prescription only
Medicine information
Doxycycline uses
Doxycycline is authorised for infections caused by organisms that respond to it, and for a small number of preventive uses. Your prescriber decides which applies to you.
- Infections spread by ticks, mites, lice and fleas, including Rocky Mountain spotted fever, typhus fever and Q fever.
- Respiratory tract infections caused by organisms such as Mycoplasma pneumoniae and Haemophilus influenzae.
- Sexually transmitted and genital infections caused by Chlamydia trachomatis, including urethritis and pelvic inflammatory disease, and lymphogranuloma venereum.
- An alternative treatment for syphilis and gonorrhoea in people who cannot take penicillin.
- Certain other bacterial infections, including cholera, brucellosis, plague, tularaemia and some eye and skin infections.
- Adjunctive treatment in severe acne, alongside other measures.
- Prevention of malaria caused by Plasmodium falciparum for short-term travellers.
- Post-exposure treatment to reduce the chance of disease after exposure to inhalational anthrax.
Your prescriber may use doxycycline for other infections. Follow their instructions, not this page.
How to use doxycycline
Take doxycycline exactly as prescribed, and pay attention to how you swallow it — doxycycline can irritate the gullet if it sticks on the way down.
- Swallow the capsule whole with a full glass of water. Do not open or chew it.
- Stay sitting or standing upright for at least 30 minutes afterwards, and do not take a dose immediately before lying down or going to bed.
- You can take doxycycline with food or milk if it upsets your stomach; food does not meaningfully reduce how much is absorbed.
- Keep antacids, iron tablets, calcium and magnesium supplements, and bismuth products at least two hours apart from your dose — they bind doxycycline and stop it being absorbed.
- For most infections the label gives a usual adult dose of 200 mg on the first day, then 100 mg a day, with more in severe infections. Your prescriber sets yours.
- For malaria prevention, the label gives 100 mg once daily, started 1 to 2 days before travel, continued daily during travel and for 4 weeks after leaving the malarious area.
- Finish the whole course even if you feel better, unless your prescriber tells you to stop.
- Use sun protection. Cover up, wear sunglasses and use sunscreen, and avoid sunlamps and tanning beds while you are taking it.
If you miss a dose
Take the missed dose as soon as you remember, with a full glass of water and sitting upright. If your next dose is almost due, skip the one you missed — do not take two at once.
Storage
Keep the capsules in their original container, tightly closed, at room temperature, away from light, damp and heat. Keep out of the sight and reach of children.
Doxycycline side effects
Most people complete a course without much trouble. Tell your prescriber or pharmacist about anything that bothers you, and about any rash or swallowing pain straight away.
Common
Serious — seek urgent care
- Pain on swallowing, chest pain behind the breastbone, or a feeling of the capsule stuck — this can be inflammation or ulceration of the gullet. Stop and contact your prescriber.
- Severe headache with blurred or double vision, or vision loss — this can be raised pressure around the brain (intracranial hypertension). Seek urgent care.
- Severe, watery or bloody diarrhoea with cramps, during treatment or up to two months after it — possible Clostridioides difficile colitis. Seek urgent care.
- Severe skin reaction — blistering, peeling skin, mouth sores, or a spreading rash with fever (Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS). Stop and seek urgent care.
- Swelling of the face, lips, tongue or throat, or difficulty breathing. Call emergency services.
- Yellowing of the skin or eyes, dark urine, or pain under the right ribs — possible liver injury. Seek urgent care.
Warnings
- Doxycycline is not used in children under 8 years old except in severe or life-threatening conditions where no alternative exists, because tetracyclines can permanently stain developing teeth and affect bone growth.
- Doxycycline can harm a developing baby. Tell your prescriber if you are pregnant, might be pregnant, or are planning a pregnancy. It also passes into breast milk.
- Do not take doxycycline if you have had an allergic reaction to any tetracycline antibiotic.
- Expect to sunburn more easily. Stop and contact your prescriber if your skin reacts — photosensitivity can be severe.
- Take it with a full glass of water and stay upright for at least 30 minutes. Oesophagitis and oesophageal ulceration have been reported, particularly when a dose is taken just before bed.
- Interaction: doxycycline may reduce the reliability of hormonal contraception. Use an additional non-hormonal method during the course and for a short period afterwards.
- Interaction: antacids, iron, calcium, magnesium and bismuth block absorption. Doxycycline can also increase the effect of warfarin, and barbiturates, carbamazepine and phenytoin can lower doxycycline levels.
- Doxycycline for malaria prevention does not replace bite avoidance. Keep using repellent and nets, and see a doctor promptly for any fever during or after travel.
Doxycycline FAQs
How long does doxycycline take to work?
For an acute bacterial infection, many people start to feel better within a few days, though it depends on the infection. For acne it is much slower — improvement is usually judged over weeks to months rather than days, and doxycycline is an adjunct to other treatment rather than a treatment on its own. In every case, finish the full course. Stopping early because symptoms settled lets the surviving bacteria regrow and encourages resistance. If you are getting worse, or are no better after a few days, contact your prescriber.
Why can't I lie down after taking doxycycline?
Because doxycycline is irritant if it lingers in the gullet. The label reports rare cases of oesophagitis and oesophageal ulceration, mostly in people who swallowed a dose with too little water or took it immediately before bed. The fix is simple: a full glass of water with the capsule, and stay sitting or standing for at least 30 minutes afterwards. If you get pain on swallowing or a burning pain behind the breastbone, stop and contact your prescriber rather than pushing through the course.
Does doxycycline make you more sensitive to the sun?
Yes, and it is one of the more common reasons people stop it. Doxycycline causes photosensitivity — an exaggerated sunburn reaction that can appear after much less sun than usual, including through cloud and on a bright winter day. The label advises avoiding excessive sunlight and artificial ultraviolet light and stopping the drug if a skin reaction occurs. Cover up, use a high-factor sunscreen, wear sunglasses, and avoid sunbeds entirely. If you are travelling somewhere sunny for malaria prevention, plan for this before you go.
Can I drink alcohol while taking doxycycline?
There is no reaction between alcohol and doxycycline of the sort that exists with metronidazole. Heavy or chronic drinking is a different matter: it speeds up how quickly the liver clears doxycycline, which can lower the level in your body and undermine the treatment, and alcohol will not help the nausea or stomach upset that doxycycline sometimes causes. If you drink regularly or have liver problems, mention it to your prescriber or our pharmacist so they can factor it into the dose and the choice of antibiotic.
Can I buy doxycycline online without a prescription?
No. Doxycycline is a prescription-only medicine and we dispense it only against a valid prescription from your licensed prescriber. Choosing the right antibiotic, the right dose and the right length of course needs a diagnosis, and doxycycline is not appropriate in pregnancy or in young children. A licensed pharmacist reviews every order here, checks it against your other medicines and your allergies, and will contact your prescriber if anything needs clarifying. Any site offering to skip the prescription is not operating lawfully.
What strengths and pack sizes do you dispense, and what does it cost?
We dispense doxycycline as 100 mg (10 tabs). The current price for each pack is shown on this page and again in your cart before you pay, with no membership fee and no tiers. Stock may be branded or generic on any given day, depending on what is in supply; the active ingredient, the strength and the pack size are what the label says either way. What we dispense is set by your prescription rather than by what you select, so if the quantity on your prescription differs from the pack you picked, our pharmacist will contact you before anything is sent.
Where do you ship doxycycline, and how long does delivery take?
We dispense only where we are licensed to dispense. The checkout tells you whether we can ship to your address before you pay, and if we cannot, you will not be charged. Delivery timing depends on your address and on how quickly the prescription can be verified. If you need doxycycline for malaria prevention, order well before you travel — the label asks you to start 1 to 2 days before entering the malarious area, and you do not want that squeezed by shipping time.
Can I take doxycycline in pregnancy or while breastfeeding?
Doxycycline is generally avoided in pregnancy. Tetracyclines cross the placenta, can affect the developing baby's teeth and bones, and the label warns that doxycycline can cause fetal harm. It also passes into breast milk. That does not make it an absolute bar in every situation — for a small number of severe infections a prescriber may judge the balance differently — but the decision is theirs, not something to work out from a product page. Tell your prescriber and our pharmacist if you are pregnant, might be, or are breastfeeding.
- Strengths
- 100 mg, in strips of 10
- Pack sizes
Pack Price 100 mg · 10 tabs $7.50 - Type of medicine
- Tetracycline-class antibacterial
- SKU
- CD-DOX-RX
- Storage
- Keep the capsules in their original container, tightly closed, at room temperature, away from light, damp and heat. Keep out of the sight and reach of children.
- Prescription status
- Prescription required
- Manufacturer packaging
- Sealed, batch number on the label
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This information is a summary and does not replace the patient information leaflet or your prescriber's advice. Pharmacist review pending.


























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